Single-chain antibody

{
  "id": "MLC-T-CHM-010894",
  "term": "Single-chain antibody",
  "field": "Chemistry",
  "definition": "A recombinant antibody fragment consisting of the variable regions of the heavy and light chains connected by a flexible peptide linker. This engineered molecule retains the antigen-binding specificity of the parent antibody but is smaller and easier to produce. Single-chain antibodies are widely used in research and therapeutic applications.",
  "subject": "Chemistry and Human Health",
  "see_also": [
    "Fv fragment",
    "heavy chain",
    "light chain",
    "variable region"
  ],
  "references": [
    "PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1245 (https://doi.org/10.1351/PAC-REC-11-06-03)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/single-chain-antibody/"
}