Mast cell

{
  "id": "MLC-T-CHM-007013",
  "term": "Mast cell",
  "field": "Chemistry",
  "definition": "A type of granulocyte found in connective tissues throughout the body, containing granules rich in histamine and heparin. Upon activation, typically by the cross-linking of surface-bound immunoglobulin E (IgE) antibodies, mast cells degranulate and release these mediators. This process initiates an inflammatory response characteristic of allergic reactions and anaphylaxis.",
  "synonyms": [
    "mastocyte"
  ],
  "subject": "Chemistry and Human Health",
  "see_also": [
    "allergic",
    "immunoglobulin E",
    "leukotriene"
  ],
  "references": [
    "PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1210 (https://doi.org/10.1351/PAC-REC-11-06-03)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/mast-cell/"
}