Mast cell activation disorder

{
  "id": "MLC-T-CHM-007014",
  "term": "Mast cell activation disorder",
  "field": "Chemistry",
  "definition": "A group of conditions characterized by the inappropriate activation and release of mediators from mast cells, leading to a variety of symptoms affecting multiple organ systems. This disorder can manifest as recurrent episodes of anaphylaxis, flushing, urticaria, and gastrointestinal issues. It is distinct from mastocytosis, which involves an abnormal proliferation of mast cells.",
  "synonyms": [
    "mast cell activation syndrome"
  ],
  "subject": "Chemistry and Human Health",
  "see_also": [
    "bone marrow",
    "mast cell",
    "mastocytosis",
    "systemic"
  ],
  "references": [
    "PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1211 (https://doi.org/10.1351/PAC-REC-11-06-03)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/mast-cell-activation-disorder/"
}