Contact urticaria

{
  "id": "MLC-T-CHM-002485",
  "term": "Contact urticaria",
  "field": "Chemistry",
  "definition": "A localized skin reaction characterized by the rapid appearance of wheals, erythema, and itching following direct contact with a specific substance. This immediate hypersensitivity response is mediated by mast cell degranulation and histamine release. Reactions can be immunologic, non-immunologic, or indeterminate, with symptoms appearing within minutes to an hour of exposure.",
  "subject": "Chemistry and Human Health",
  "see_also": [
    "hives"
  ],
  "references": [
    "PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1149 (https://doi.org/10.1351/PAC-REC-11-06-03)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/contact-urticaria/"
}