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Anaphylatoxin

Term · Chemistry · MLC-T-CHM-000567

A peptide fragment, such as C3a, C4a, or C5a, generated during complement activation that induces inflammatory responses. These fragments bind to specific receptors on mast cells and basophils, causing degranulation and the release of histamine and other mediators. They also act as chemoattractants for phagocytic cells.

Table 1. Record
IdentifierMLC-T-CHM-000567
FieldChemistry
SubjectChemistry and Human Health
ReferencesPAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1122 (https://doi.org/10.1351/PAC-REC-11-06-03)
See alsoChemotaxis; Degranulation; Mast cell
Record as JSON
{
  "id": "MLC-T-CHM-000567",
  "term": "Anaphylatoxin",
  "field": "Chemistry",
  "definition": "A peptide fragment, such as C3a, C4a, or C5a, generated during complement activation that induces inflammatory responses. These fragments bind to specific receptors on mast cells and basophils, causing degranulation and the release of histamine and other mediators. They also act as chemoattractants for phagocytic cells.",
  "subject": "Chemistry and Human Health",
  "see_also": [
    "chemotaxis",
    "degranulation",
    "mast cell"
  ],
  "references": [
    "PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1122 (https://doi.org/10.1351/PAC-REC-11-06-03)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/anaphylatoxin/"
}

Record 607 of 13,676 in Chemistry terminology (MLC-0109). Request the full dataset.