fMLP peptide

{
  "id": "MLC-T-CHM-004548",
  "term": "fMLP peptide",
  "field": "Chemistry",
  "definition": "A synthetic peptide, N-formylmethionyl-leucyl-phenylalanine, that mimics bacterial N-formylated peptides and acts as a potent chemoattractant for phagocytic cells, particularly neutrophils. It binds to specific G protein-coupled receptors on immune cells, initiating a signaling cascade that leads to chemotaxis, degranulation, and the production of reactive oxygen species. This peptide is widely used in immunology research to study neutrophil activation and inflammatory responses.",
  "subject": "Chemistry and Human Health",
  "see_also": [
    "chemotactic factor",
    "chemotaxis",
    "neutrophil activation"
  ],
  "references": [
    "PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1165 (https://doi.org/10.1351/PAC-REC-11-06-03)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/fmlp-peptide/"
}