Passive cutaneous anaphylaxis test

{
  "id": "MLC-T-CHM-008530",
  "term": "Passive cutaneous anaphylaxis test",
  "field": "Chemistry",
  "definition": "An in vivo assay used to detect the presence of allergen-specific IgE antibodies in serum. Serum from a sensitized individual is injected intradermally into a naive recipient animal, followed by intravenous challenge with the allergen and a dye. A positive reaction is indicated by local extravasation of the dye due to mast cell degranulation.",
  "synonyms": [
    "PCA test"
  ],
  "subject": "Chemistry and Human Health",
  "see_also": [
    "allergen"
  ],
  "references": [
    "PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1225 (https://doi.org/10.1351/PAC-REC-11-06-03)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/passive-cutaneous-anaphylaxis-test/"
}