Anaphylactic shock

{
  "id": "MLC-T-CHM-000565",
  "term": "Anaphylactic shock",
  "field": "Chemistry",
  "definition": "A severe, life-threatening systemic allergic reaction that occurs rapidly after exposure to an allergen. It is characterized by a sudden drop in blood pressure and circulatory collapse, resulting from widespread vasodilation and increased vascular permeability triggered by a massive release of histamine and other mediators from mast cells and basophils. Anaphylactic shock requires immediate medical intervention, including the administration of epinephrine.",
  "subject": "Chemistry and Human Health",
  "see_also": [
    "anaphylaxis",
    "angioedema",
    "immune system"
  ],
  "references": [
    "PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1122 (https://doi.org/10.1351/PAC-REC-11-06-03)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/anaphylactic-shock/"
}