Toxic shock syndrome

{
  "id": "MLC-T-CHM-012159",
  "term": "Toxic shock syndrome",
  "field": "Chemistry",
  "definition": "A severe and potentially fatal condition caused by bacterial toxins, primarily from Staphylococcus aureus or Streptococcus pyogenes. It is characterized by a sudden onset of fever, rash, hypotension, and multi-organ dysfunction. The syndrome is often associated with superantigens that trigger a massive, non-specific activation of T lymphocytes, leading to an overwhelming inflammatory response.",
  "subject": "Chemistry and Human Health",
  "see_also": [
    "CD4",
    "systemic",
    "T lymphocyte",
    "cytokine",
    "superantigen"
  ],
  "references": [
    "PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1254 (https://doi.org/10.1351/PAC-REC-11-06-03)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/toxic-shock-syndrome/"
}