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Skin sensitization test

Term · Chemistry · MLC-T-CHM-010931

An experimental procedure designed to identify substances that can induce an allergic contact dermatitis reaction upon skin exposure. These tests involve applying a substance to the skin of an animal, such as a guinea pig or mouse, and observing for an immune response after re-exposure. Common methods include the Local Lymph Node Assay (LLNA) and the Guinea Pig Maximization Test.

Table 1. Record
IdentifierMLC-T-CHM-010931
FieldChemistry
SubjectChemistry and Human Health
ReferencesPAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1245 (https://doi.org/10.1351/PAC-REC-11-06-03)
See alsoBuehler assay; Guinea pig maximization test; Hypersensitivity
Record as JSON
{
  "id": "MLC-T-CHM-010931",
  "term": "Skin sensitization test",
  "field": "Chemistry",
  "definition": "An experimental procedure designed to identify substances that can induce an allergic contact dermatitis reaction upon skin exposure. These tests involve applying a substance to the skin of an animal, such as a guinea pig or mouse, and observing for an immune response after re-exposure. Common methods include the Local Lymph Node Assay (LLNA) and the Guinea Pig Maximization Test.",
  "subject": "Chemistry and Human Health",
  "see_also": [
    "Buehler assay",
    "guinea pig maximization test",
    "hypersensitivity"
  ],
  "references": [
    "PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1245 (https://doi.org/10.1351/PAC-REC-11-06-03)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/skin-sensitization-test/"
}

Record 11,641 of 13,676 in Chemistry terminology (MLC-0109). Request the full dataset.