Buehler assay

{
  "id": "MLC-T-CHM-001527",
  "term": "Buehler assay",
  "field": "Chemistry",
  "definition": "A method used to assess the potential of a substance to cause skin sensitization, primarily in guinea pigs. The test involves repeated topical applications of the test substance, followed by a challenge application to determine if an allergic contact dermatitis reaction occurs. This assay is a standard method for identifying contact allergens.",
  "synonyms": [
    "Buehler test"
  ],
  "subject": "Chemistry and Human Health",
  "see_also": [
    "skin sensitization test",
    "challenge",
    "contact dermatitis"
  ],
  "references": [
    "PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1136 (https://doi.org/10.1351/PAC-REC-11-06-03)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/buehler-assay/"
}