Clastogenesis

{
  "id": "MLC-T-CHM-002105",
  "term": "Clastogenesis",
  "field": "Chemistry",
  "definition": "The process by which a clastogen induces structural damage to chromosomes, resulting in breaks, deletions, inversions, or translocations. This phenomenon can lead to genetic instability, cell cycle arrest, or apoptosis. Clastogenesis is a key mechanism underlying the genotoxic effects of many environmental toxins and therapeutic agents.",
  "subject": "Chemistry and Human Health",
  "references": [
    "PAC, 2007, 79, 1153. 'Glossary of terms used in toxicology, 2nd edition (IUPAC Recommendations 2007)' on page 1191 (https://doi.org/10.1351/pac200779071153)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/clastogenesis/"
}