Damage to deoxyribonucleic acid

{
  "id": "MLC-T-CHM-002853",
  "term": "Damage to deoxyribonucleic acid",
  "field": "Chemistry",
  "definition": "Any alteration to the chemical structure of deoxyribonucleic acid (DNA) that can impair its function or replication. This can include single- or double-strand breaks, base modifications, cross-links, or adduct formation. DNA damage can arise from endogenous processes like oxidative stress or from exogenous agents such as radiation, genotoxic chemicals, or certain viruses.",
  "synonyms": [
    "damage to DNA",
    "DNA damage"
  ],
  "subject": "Analytical Chemistry",
  "references": [
    "PAC, 2018, 90, 1121. 'Terminology of bioanalytical methods (IUPAC Recommendations 2018)' on page 1144 (https://doi.org/10.1515/pac-2016-1120)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/damage-to-deoxyribonucleic-acid/"
}