Deoxyribonucleic acid mismatch

{
  "id": "MLC-T-CHM-003014",
  "term": "Deoxyribonucleic acid mismatch",
  "field": "Chemistry",
  "definition": "A defect in double-stranded DNA in which the helix contains one or more base pairs other than the standard A-T and G-C Watson-Crick pairs, such as A-C, G-T, A-G or C-T. Mismatches arise from replication errors, deamination or recombination, and they are detected and corrected by mismatch repair. The same term describes a probe or primer base that does not pair with its template.",
  "synonyms": [
    "DNA mismatch",
    "mismatch in DNA",
    "multi-base mismatch",
    "single mismatch"
  ],
  "subject": "Analytical Chemistry",
  "see_also": [
    "base pair",
    "double helix"
  ],
  "references": [
    "PAC, 2018, 90, 1121. 'Terminology of bioanalytical methods (IUPAC Recommendations 2018)' on page 1145 (https://doi.org/10.1515/pac-2016-1120)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/deoxyribonucleic-acid-mismatch/"
}