Origin of replication

{
  "id": "MLC-T-CHM-008328",
  "term": "Origin of replication",
  "field": "Chemistry",
  "definition": "A specific sequence of deoxyribonucleic acid (DNA) where replication of a chromosome or plasmid begins. This site serves as a binding point for initiator proteins, which unwind the DNA double helix to form a replication bubble. In bacteria, there is typically one origin of replication per chromosome.",
  "synonyms": [
    "ori"
  ],
  "subject": "Chemistry and the Environment",
  "see_also": [
    "deoxyribonucleic acids",
    "chromosome",
    "plasmid",
    "replication",
    "sequence"
  ],
  "references": [
    "PAC, 1992, 64, 143. 'Glossary for chemists of terms used in biotechnology (IUPAC Recommendations 1992)' on page 162 (https://doi.org/10.1351/pac199264010143)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/origin-of-replication/"
}