Dermal irritation

{
  "id": "MLC-T-CHM-003053",
  "term": "Dermal irritation",
  "field": "Chemistry",
  "definition": "A localized inflammatory response of the skin to direct contact with a chemical substance, characterized by redness, swelling, itching, or pain. This reaction does not involve an immune system sensitization but is a direct toxic effect on skin cells. It is a common endpoint in toxicology studies for assessing chemical safety.",
  "subject": "Chemistry and Human Health",
  "references": [
    "PAC, 2007, 79, 1153. 'Glossary of terms used in toxicology, 2nd edition (IUPAC Recommendations 2007)' on page 1204 (https://doi.org/10.1351/pac200779071153)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/dermal-irritation/"
}