Entatic state

{
  "id": "MLC-T-CHM-003947",
  "term": "Entatic state",
  "field": "Chemistry",
  "definition": "A strained or distorted conformation of a metal ion in a metalloprotein, which is poised for reaction and has a higher potential energy than its relaxed state. This pre-organized state lowers the activation energy for subsequent chemical transformations. The entatic state hypothesis explains the high catalytic efficiency of many metalloenzymes.",
  "subject": "Inorganic Chemistry",
  "references": [
    "PAC, 1997, 69, 1251. 'Glossary of terms used in bioinorganic chemistry (IUPAC Recommendations 1997)' on page 1272 (https://doi.org/10.1351/pac199769061251)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/entatic-state/"
}