Heparin-induced thrombocytopenia

{
  "id": "MLC-T-CHM-005212",
  "term": "Heparin-induced thrombocytopenia",
  "field": "Chemistry",
  "definition": "An adverse drug reaction characterized by a decrease in platelet count following exposure to heparin, an anticoagulant medication. This condition involves the formation of antibodies against complexes of heparin and platelet factor 4, leading to platelet activation and aggregation. It can result in both thrombotic complications and a reduction in circulating platelets.",
  "subject": "Chemistry and Human Health",
  "see_also": [
    "platelet"
  ],
  "references": [
    "PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1174 (https://doi.org/10.1351/PAC-REC-11-06-03)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/heparin-induced-thrombocytopenia/"
}