Hereditary angioneurotic edema

{
  "id": "MLC-T-CHM-005218",
  "term": "Hereditary angioneurotic edema",
  "field": "Chemistry",
  "definition": "A rare genetic disorder characterized by recurrent episodes of severe swelling (edema) in the limbs, face, intestinal tract, or airway. The condition results from a deficiency or dysfunction of the C1 inhibitor protein, a component of the complement system that regulates inflammation. Attacks are not associated with the urticaria (hives) seen in allergic reactions and can be life-threatening if swelling obstructs the airway.",
  "subject": "Chemistry and Human Health",
  "see_also": [
    "C1 inhibitor",
    "complement system"
  ],
  "references": [
    "PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1174 (https://doi.org/10.1351/PAC-REC-11-06-03)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/hereditary-angioneurotic-edema/"
}