Huisgen reaction

{
  "id": "MLC-T-CHM-005414",
  "term": "Huisgen reaction",
  "field": "Chemistry",
  "definition": "A cycloaddition process involving the combination of a three-atom component, known as a 1,3-dipole, with a two-atom component, the dipolarophile. This reaction constructs a five-membered heterocyclic ring system. A prominent example is the reaction of an organic azide with an alkyne to produce a 1,2,3-triazole, which forms the basis of copper-catalyzed azide-alkyne cycloaddition (CuAAC) click chemistry.",
  "subject": "Organic and Biomolecular Chemistry",
  "references": [
    "PAC, 2022, 94, 353. 'Glossary of terms used in physical organic chemistry (IUPAC Recommendations 2021)' on page 434 (https://doi.org/10.1515/pac-2018-1010)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/huisgen-reaction/"
}