Intolerance

{
  "id": "MLC-T-CHM-006004",
  "term": "Intolerance",
  "field": "Chemistry",
  "definition": "A physiological response to a substance that does not involve the immune system, distinguishing it from an allergy. These non-immunological reactions are often caused by an inability to metabolize or process a specific compound due to an enzyme deficiency. For example, lactose intolerance results from a deficiency of the lactase enzyme, leading to gastrointestinal symptoms after consuming dairy products.",
  "subject": "Chemistry and Human Health",
  "see_also": [
    "allergy"
  ],
  "references": [
    "PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1195 (https://doi.org/10.1351/PAC-REC-11-06-03)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/intolerance/"
}