Primary myxedema

{
  "id": "MLC-T-CHM-009436",
  "term": "Primary myxedema",
  "field": "Chemistry",
  "definition": "A condition characterized by severe hypothyroidism resulting from a dysfunction of the thyroid gland itself. This leads to a marked decrease in the production of thyroid hormones, often due to autoimmune destruction of the thyroid tissue. Symptoms include fatigue, weight gain, cold intolerance, and a characteristic swelling of the skin and subcutaneous tissues.",
  "subject": "Chemistry and Human Health",
  "see_also": [
    "autoimmune",
    "autoimmune thyroiditis"
  ],
  "references": [
    "PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1234 (https://doi.org/10.1351/PAC-REC-11-06-03)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/primary-myxedema/"
}