Thyroid peroxidase

{
  "id": "MLC-T-CHM-012051",
  "term": "Thyroid peroxidase",
  "field": "Chemistry",
  "definition": "An enzyme expressed in the thyroid gland that facilitates the synthesis of thyroid hormones. It catalyzes the iodination of tyrosine residues on the thyroglobulin protein and the coupling of these iodinated tyrosines to form thyroxine (T4) and triiodothyronine (T3). In autoimmune thyroid diseases like Hashimoto's thyroiditis, this enzyme becomes a primary autoantigen, targeted by the body's own immune system.",
  "subject": "Chemistry and Human Health",
  "see_also": [
    "autoantigen",
    "autoimmune disease"
  ],
  "references": [
    "PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1254 (https://doi.org/10.1351/PAC-REC-11-06-03)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/thyroid-peroxidase/"
}