Autoantigen

{
  "id": "MLC-T-CHM-000961",
  "term": "Autoantigen",
  "field": "Chemistry",
  "definition": "A normal self-component, such as a protein or nucleic acid, that is recognized as foreign by the immune system, leading to an autoimmune response. These molecules trigger the production of autoantibodies and activation of self-reactive T lymphocytes. Autoantigens are central to the pathogenesis of autoimmune diseases.",
  "subject": "Chemistry and Human Health",
  "see_also": [
    "antigenic",
    "B lymphocyte",
    "T lymphocyte",
    "autoantibody",
    "autoimmune",
    "cardiolipin",
    "self-tolerance"
  ],
  "references": [
    "PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1129 (https://doi.org/10.1351/PAC-REC-11-06-03)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/autoantigen/"
}