MLchartDataset catalogue

Natural autoantibodies

Term · Chemistry · MLC-T-CHM-007772

Immunoglobulin molecules produced by the immune system without prior exogenous antigenic stimulation. These antibodies are present in healthy individuals and can react with self-antigens, contributing to immune surveillance and homeostasis. They are typically low-affinity and polyspecific, distinguishing them from pathogenic autoantibodies that cause autoimmune diseases.

Table 1. Record
IdentifierMLC-T-CHM-007772
FieldChemistry
SubjectChemistry and Human Health
ReferencesPAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1218 (https://doi.org/10.1351/PAC-REC-11-06-03)
See alsoCD5+ B lymphocyte; T lymphocyte; Autoantigen; Autoimmune hemolytic anemia; Autoimmunity; Immunoglobulin M; Isotype; Immunological tolerance
Record as JSON
{
  "id": "MLC-T-CHM-007772",
  "term": "Natural autoantibodies",
  "field": "Chemistry",
  "definition": "Immunoglobulin molecules produced by the immune system without prior exogenous antigenic stimulation. These antibodies are present in healthy individuals and can react with self-antigens, contributing to immune surveillance and homeostasis. They are typically low-affinity and polyspecific, distinguishing them from pathogenic autoantibodies that cause autoimmune diseases.",
  "subject": "Chemistry and Human Health",
  "see_also": [
    "CD5+ B lymphocyte",
    "T lymphocyte",
    "autoantigen",
    "autoimmune hemolytic anemia",
    "autoimmunity",
    "immunoglobulin M",
    "isotype",
    "immunological tolerance"
  ],
  "references": [
    "PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1218 (https://doi.org/10.1351/PAC-REC-11-06-03)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/natural-autoantibodies/"
}

Record 8,252 of 13,676 in Chemistry terminology (MLC-0109). Request the full dataset.