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Islet cell antibodies

Term · Chemistry · MLC-T-CHM-013217

Autoantibodies directed against components of the pancreatic islet cells, particularly the beta cells that produce insulin. Their presence indicates an autoimmune response targeting the pancreas, which is characteristic of Type 1 diabetes mellitus. These antibodies are often detected in the serum of individuals before the clinical onset of the disease.

Table 1. Record
IdentifierMLC-T-CHM-013217
FieldChemistry
SubjectChemistry and Human Health
ReferencesPAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1196 (https://doi.org/10.1351/PAC-REC-11-06-03)
See alsoAutoantibody; Diabetes mellitus type 1; Indirect immunofluorescence
Record as JSON
{
  "id": "MLC-T-CHM-013217",
  "term": "Islet cell antibodies",
  "field": "Chemistry",
  "definition": "Autoantibodies directed against components of the pancreatic islet cells, particularly the beta cells that produce insulin. Their presence indicates an autoimmune response targeting the pancreas, which is characteristic of Type 1 diabetes mellitus. These antibodies are often detected in the serum of individuals before the clinical onset of the disease.",
  "subject": "Chemistry and Human Health",
  "see_also": [
    "autoantibody",
    "diabetes mellitus type 1",
    "indirect immunofluorescence"
  ],
  "references": [
    "PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1196 (https://doi.org/10.1351/PAC-REC-11-06-03)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/islet-cell-antibodies/"
}

Record 6,544 of 13,676 in Chemistry terminology (MLC-0109). Request the full dataset.