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Autoimmune polyendocrine syndrome type 1 or 2

Term · Chemistry · MLC-T-CHM-000981

A group of rare disorders characterized by the simultaneous occurrence of autoimmune diseases affecting multiple endocrine glands. Type 1 involves chronic mucocutaneous candidiasis, hypoparathyroidism, and Addison disease, while Type 2 typically includes Addison disease, autoimmune thyroid disease, and type 1 diabetes mellitus. These syndromes result from a breakdown in immune tolerance.

Table 1. Record
IdentifierMLC-T-CHM-000981
FieldChemistry
SubjectChemistry and Human Health
ReferencesPAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1130 (https://doi.org/10.1351/PAC-REC-11-06-03)
See alsoAddison disease; Hashimoto thyroiditis; Autoimmune; Candidiasis; Diabetes mellitus type 1; Human leukocyte antigen; Mucosa; Spleen
Record as JSON
{
  "id": "MLC-T-CHM-000981",
  "term": "Autoimmune polyendocrine syndrome type 1 or 2",
  "field": "Chemistry",
  "definition": "A group of rare disorders characterized by the simultaneous occurrence of autoimmune diseases affecting multiple endocrine glands. Type 1 involves chronic mucocutaneous candidiasis, hypoparathyroidism, and Addison disease, while Type 2 typically includes Addison disease, autoimmune thyroid disease, and type 1 diabetes mellitus. These syndromes result from a breakdown in immune tolerance.",
  "subject": "Chemistry and Human Health",
  "see_also": [
    "Addison disease",
    "Hashimoto thyroiditis",
    "autoimmune",
    "candidiasis",
    "diabetes mellitus type 1",
    "human leukocyte antigen",
    "mucosa",
    "spleen"
  ],
  "references": [
    "PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1130 (https://doi.org/10.1351/PAC-REC-11-06-03)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/autoimmune-polyendocrine-syndrome-type-1-or-2/"
}

Record 1,056 of 13,678 in Chemistry terminology (MLC-0109). Request the full dataset.