Lock mass

{
  "id": "MLC-T-CHM-006744",
  "term": "Lock mass",
  "field": "Chemistry",
  "definition": "A precisely known mass-to-charge ratio of a reference compound introduced into a mass spectrometer to provide continuous internal calibration during an analysis. This reference signal allows for real-time correction of mass drift, improving the accuracy and precision of mass measurements. Perfluorotributylamine (PFTBA) is a common lock mass standard.",
  "subject": "Analytical Chemistry",
  "references": [
    "PAC, 2013, 85, 1515. 'Definitions of terms relating to mass spectrometry (IUPAC Recommendations 2013)' on page 1561 (https://doi.org/10.1351/PAC-REC-06-04-06)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/lock-mass/"
}