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Moving average method

Term · Chemistry · MLC-T-CHM-007605

A computational method for estimating a median lethal or effective concentration (LC50, EC50) or a median lethal dose (LD50) from quantal toxicity test data. It smooths the response proportions by averaging over adjacent test concentrations and then interpolates to the concentration giving a 50% response. The calculation is simplest when the concentrations form a geometric series with equal numbers of organisms at each.

Table 1. Record
IdentifierMLC-T-CHM-007605
FieldChemistry
SubjectChemistry and Human Health
ReferencesPAC, 2009, 81, 829. 'Glossary of terms used in ecotoxicology (IUPAC Recommendations 2009)' on page 918 (https://doi.org/10.1351/PAC-REC-08-07-09)
Record as JSON
{
  "id": "MLC-T-CHM-007605",
  "term": "Moving average method",
  "field": "Chemistry",
  "definition": "A computational method for estimating a median lethal or effective concentration (LC50, EC50) or a median lethal dose (LD50) from quantal toxicity test data. It smooths the response proportions by averaging over adjacent test concentrations and then interpolates to the concentration giving a 50% response. The calculation is simplest when the concentrations form a geometric series with equal numbers of organisms at each.",
  "subject": "Chemistry and Human Health",
  "references": [
    "PAC, 2009, 81, 829. 'Glossary of terms used in ecotoxicology (IUPAC Recommendations 2009)' on page 918 (https://doi.org/10.1351/PAC-REC-08-07-09)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/moving-average-method/"
}

Record 8,068 of 13,676 in Chemistry terminology (MLC-0109). Request the full dataset.