Multitarget-directed ligand

{
  "id": "MLC-T-CHM-007688",
  "term": "Multitarget-directed ligand",
  "field": "Chemistry",
  "definition": "A single chemical entity designed to interact with two or more distinct biological targets that are implicated in a disease pathway. This approach aims to achieve a synergistic therapeutic effect or to address the multifactorial nature of complex diseases. Such ligands are developed to overcome the limitations of single-target drugs.",
  "synonyms": [
    "multitarget drug"
  ],
  "subject": "Chemistry and Human Health",
  "see_also": [
    "molecular target"
  ],
  "references": [
    "PAC, 2013, 85, 1725. 'Glossary of terms used in medicinal chemistry. Part II (IUPAC Recommendations 2013)' on page 1742 (https://doi.org/10.1351/PAC-REC-12-11-23)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/multitarget-directed-ligand/"
}