N-terminal analysis

{
  "id": "MLC-T-CHM-008090",
  "term": "N-terminal analysis",
  "field": "Chemistry",
  "definition": "A biochemical method used to determine the amino acid sequence starting from the N-terminus (amino-terminus) of a protein or peptide. This analysis typically involves sequential cleavage of amino acids from the N-terminus, followed by their identification. The Edman degradation is a classic example of an N-terminal analysis technique, providing sequence information for up to 50-60 amino acid residues.",
  "subject": "Analytical Chemistry",
  "see_also": [
    "Edman degradation",
    "N-terminus"
  ],
  "references": [
    "PAC, 2018, 90, 1121. 'Terminology of bioanalytical methods (IUPAC Recommendations 2018)' on page 1157 (https://doi.org/10.1515/pac-2016-1120)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/n-terminal-analysis/"
}