Protein sequencer

{
  "id": "MLC-T-CHM-009585",
  "term": "Protein sequencer",
  "field": "Chemistry",
  "definition": "An automated instrument that determines the primary structure of a protein, which is its amino acid sequence. The device performs sequential chemical reactions, most commonly Edman degradation, to cleave, separate, and identify one amino acid at a time from the N-terminus of the polypeptide chain. Modern sequencers can analyze picomole quantities of a protein and determine the sequence of 20 to 30 amino acids in a single run.",
  "subject": "Analytical Chemistry",
  "see_also": [
    "Edman degradation",
    "N-terminal analysis"
  ],
  "references": [
    "PAC, 2018, 90, 1121. 'Terminology of bioanalytical methods (IUPAC Recommendations 2018)' on page 1162 (https://doi.org/10.1515/pac-2016-1120)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/protein-sequencer/"
}