Neuropathy target esterase

{
  "id": "MLC-T-CHM-007889",
  "term": "Neuropathy target esterase",
  "field": "Chemistry",
  "definition": "An enzyme found in the nervous system that is a primary target for certain organophosphate compounds, leading to delayed neurotoxicity. Inhibition of this enzyme by specific organophosphates initiates a cascade of events that can result in a characteristic delayed polyneuropathy. The activity of this enzyme is often measured in toxicology studies to assess potential neurotoxic effects.",
  "synonyms": [
    "neurotoxic esterase"
  ],
  "subject": "Chemistry and Human Health",
  "see_also": [
    "neuropathy",
    "organophosphate"
  ],
  "references": [
    "PAC, 2015, 87, 841. 'IUPAC Glossary of terms used in neurotoxicology (IUPAC Recommendations 2015)' on page 889 (https://doi.org/10.1515/pac-2015-0103)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/neuropathy-target-esterase/"
}