Neurotoxic esterase assay

{
  "id": "MLC-T-CHM-007896",
  "term": "Neurotoxic esterase assay",
  "field": "Chemistry",
  "definition": "A biochemical test used to measure the activity of neuropathy target esterase (NTE) in nervous tissue, typically from hens. This assay is employed to assess the potential neurotoxicity of organophosphate compounds, which can inhibit NTE and lead to delayed polyneuropathy. A reduction in NTE activity below a certain threshold indicates a risk of neurotoxic effects.",
  "synonyms": [
    "NTE assay"
  ],
  "subject": "Chemistry and Human Health",
  "see_also": [
    "hen test",
    "neuropathy",
    "neuropathy target esterase",
    "organophosphate"
  ],
  "references": [
    "PAC, 2015, 87, 841. 'IUPAC Glossary of terms used in neurotoxicology (IUPAC Recommendations 2015)' on page 890 (https://doi.org/10.1515/pac-2015-0103)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/neurotoxic-esterase-assay/"
}