No observed adverse effect level

{
  "id": "MLC-T-CHM-007977",
  "term": "No observed adverse effect level",
  "field": "Chemistry",
  "definition": "The highest dose or exposure level of a substance at which no statistically or biologically adverse effects are observed in a study population. This level is determined from experimental toxicology studies, often in animals, and is used as a reference point in risk assessment. It serves as a basis for establishing safe exposure limits for humans.",
  "subject": "Chemistry and Human Health",
  "see_also": [
    "morphology"
  ],
  "references": [
    "PAC, 1993, 65, 2003. 'Glossary for chemists of terms used in toxicology (IUPAC Recommendations 1993)' on page 2076 (https://doi.org/10.1351/pac199365092003)",
    "PAC, 2001, 73, 993. 'Risk assessment for occupational exposure to chemicals. A review of current methodology (IUPAC Technical Report)' on page 1023 (https://doi.org/10.1351/pac200173060993)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/no-observed-adverse-effect-level/"
}