Critical end-point

{
  "id": "MLC-T-CHM-002684",
  "term": "Critical end-point",
  "field": "Chemistry",
  "definition": "A specific, measurable biological or toxicological effect chosen as the primary indicator of harm in a risk assessment. This outcome is considered the most sensitive or relevant adverse effect for a given exposure. It serves as the basis for establishing safe exposure limits or regulatory standards.",
  "subject": "Chemistry and Human Health",
  "references": [
    "PAC, 2007, 79, 1153. 'Glossary of terms used in toxicology, 2nd edition (IUPAC Recommendations 2007)' on page 1199 (https://doi.org/10.1351/pac200779071153)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/critical-end-point/"
}