Critical organ

{
  "id": "MLC-T-CHM-002695",
  "term": "Critical organ",
  "field": "Chemistry",
  "definition": "The specific organ or tissue in the body that first shows adverse effects from exposure to a toxic substance, or the organ that exhibits the most severe effects at a given dose. This organ is considered the most sensitive target for a particular toxicant. For example, the liver is a common critical organ for many orally ingested toxins.",
  "subject": "Chemistry and Human Health",
  "see_also": [
    "critical concentration",
    "critical effect"
  ],
  "references": [
    "PAC, 2007, 79, 1153. 'Glossary of terms used in toxicology, 2nd edition (IUPAC Recommendations 2007)' on page 1199 (https://doi.org/10.1351/pac200779071153)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/critical-organ/"
}