Programmed-flow chromatography

{
  "id": "MLC-T-CHM-009524",
  "term": "Programmed-flow chromatography",
  "field": "Chemistry",
  "definition": "A chromatographic technique where the mobile phase flow rate is varied systematically during a separation to influence retention times and improve resolution. This approach can accelerate the elution of late-eluting components without compromising the separation of early-eluting ones. It is often used in gas chromatography and liquid chromatography to achieve better peak separation and reduce analysis time.",
  "synonyms": [
    "flow programming"
  ],
  "subject": "Analytical Chemistry",
  "references": [
    "PAC, 1993, 65, 819. 'Nomenclature for chromatography (IUPAC Recommendations 1993)' on page 827 (https://doi.org/10.1351/pac199365040819)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/programmed-flow-chromatography/"
}