Reactive nitrogen species

{
  "id": "MLC-T-CHM-009980",
  "term": "Reactive nitrogen species",
  "field": "Chemistry",
  "definition": "A group of highly reactive molecules containing nitrogen that are derived from nitric oxide or its metabolites. These species are involved in cellular signaling and defense mechanisms, but at elevated concentrations, they can induce nitrosative stress by modifying proteins, lipids, and nucleic acids. Key examples include peroxynitrite (ONOO−), nitrogen dioxide (NO2), and dinitrogen trioxide (N2O3), which are distinct from reactive oxygen species that are centered on oxygen chemistry.",
  "subject": "Chemistry and Human Health",
  "references": [
    "PAC, 2007, 79, 1153. 'Glossary of terms used in toxicology, 2nd edition (IUPAC Recommendations 2007)' on page 1294 (https://doi.org/10.1351/pac200779071153)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/reactive-nitrogen-species/"
}