Reperfusion

{
  "id": "MLC-T-CHM-010190",
  "term": "Reperfusion",
  "field": "Chemistry",
  "definition": "The restoration of blood flow to an organ or tissue that has experienced a period of ischemia, or inadequate blood supply. While necessary to prevent irreversible cell death from hypoxia, the reintroduction of oxygen can paradoxically cause additional cellular damage, a phenomenon known as reperfusion injury. This secondary injury is mediated by inflammation and the formation of reactive oxygen species, which damage lipids, proteins, and nucleic acids within the cells.",
  "subject": "Chemistry and Human Health",
  "references": [
    "PAC, 2015, 87, 841. 'IUPAC Glossary of terms used in neurotoxicology (IUPAC Recommendations 2015)' on page 902 (https://doi.org/10.1515/pac-2015-0103)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/reperfusion/"
}