Restricted-access sorbent

{
  "id": "MLC-T-CHM-010275",
  "term": "Restricted-access sorbent",
  "field": "Chemistry",
  "definition": "A type of chromatographic sorbent designed to allow small molecules to access the stationary phase while excluding larger molecules, such as proteins, from entering the pores. This enables direct injection of biological samples without extensive protein precipitation. The exclusion is based on size and sometimes hydrophobicity.",
  "subject": "Analytical Chemistry",
  "references": [
    "PAC, 2016, 88, 517. 'Glossary of terms used in extraction (IUPAC Recommendations 2016)' on page 544 (https://doi.org/10.1515/pac-2015-0903)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/restricted-access-sorbent/"
}