Distribution constant (exclusion)

{
  "id": "MLC-T-CHM-003343",
  "term": "Distribution constant (exclusion)",
  "field": "Chemistry",
  "definition": "A parameter in size-exclusion chromatography that quantifies the extent to which a solute can penetrate the pores of the stationary phase. It represents the fraction of the intraparticle volume that is accessible to the solute molecules. A value of 0 indicates complete exclusion, while a value of 1 signifies full access to the pore volume.",
  "subject": "Analytical Chemistry",
  "see_also": [
    "intraparticle volume of the column"
  ],
  "references": [
    "PAC, 2017, 90, 181. 'Terminology of separation methods (IUPAC Recommendations 2017)' on page 211 (https://doi.org/10.1515/pac-2017-0111)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/distribution-constant-exclusion/"
}