Intraparticle volume of the column

{
  "id": "MLC-T-CHM-006017",
  "term": "Intraparticle volume of the column",
  "field": "Chemistry",
  "definition": "The volume of mobile phase held inside the pores of the stationary phase particles in a column, as distinct from the interstitial volume between the particles. Together they make up the total mobile phase volume of a column packed with porous particles. Solutes small enough to enter the pores can access it, whereas very large solutes are excluded from it, which is the basis of size-exclusion chromatography.",
  "synonyms": [
    "intrastitial volume of the column",
    "stationary mobile-phase volume"
  ],
  "subject": "Analytical Chemistry",
  "see_also": [
    "retention volume"
  ],
  "references": [
    "PAC, 2017, 90, 181. 'Terminology of separation methods (IUPAC Recommendations 2017)' on page 210 (https://doi.org/10.1515/pac-2017-0111)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/intraparticle-volume-of-the-column/"
}