Returned effect of poisons

{
  "id": "MLC-T-CHM-010309",
  "term": "Returned effect of poisons",
  "field": "Chemistry",
  "definition": "A heightened response to a poison, in which the dose-effect curve shifts so that a given dose acts more strongly after the organism has been exposed repeatedly to progressively smaller doses. The same dose that once produced little effect then produces a clear one, which is the reverse of tolerance, where repeated exposure weakens the response.",
  "subject": "Chemistry and Human Health",
  "references": [
    "PAC, 2007, 79, 1153. 'Glossary of terms used in toxicology, 2nd edition (IUPAC Recommendations 2007)' on page 1301 (https://doi.org/10.1351/pac200779071153)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/returned-effect-of-poisons/"
}