Toxicophoric group

{
  "id": "MLC-T-CHM-012178",
  "term": "Toxicophoric group",
  "field": "Chemistry",
  "definition": "A specific functional group or structural feature within a molecule that is responsible for its toxic properties. This part of the molecule interacts with a biological target, such as an enzyme or receptor, initiating a chain of events that results in an adverse health effect. The nitroaromatic group (Ar-NO2) is an example of a toxicophoric group found in many compounds with mutagenic or carcinogenic activity.",
  "synonyms": [
    "toxogenic group",
    "toxophoric group"
  ],
  "subject": "Chemistry and Human Health",
  "references": [
    "PAC, 2007, 79, 1153. 'Glossary of terms used in toxicology, 2nd edition (IUPAC Recommendations 2007)' on page 1327 (https://doi.org/10.1351/pac200779071153)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/toxicophoric-group/"
}