Ames/salmonella test

{
  "id": "MLC-T-CHM-000482",
  "term": "Ames/salmonella test",
  "field": "Chemistry",
  "definition": "A biological assay used to assess the mutagenic potential of chemical compounds by observing their ability to cause mutations in specific strains of the bacterium Salmonella typhimurium. The test measures the frequency of reverse mutations that restore the bacteria's ability to synthesize histidine, indicating a mutagenic effect. It is widely used as a preliminary screening tool for carcinogens.",
  "subject": "Chemistry and the Environment",
  "see_also": [
    "mutagen",
    "strain"
  ],
  "references": [
    "PAC, 1990, 62, 2167. 'Glossary of atmospheric chemistry terms (Recommendations 1990)' on page 2173 (https://doi.org/10.1351/pac199062112167)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/ames-salmonella-test/"
}