Trisomy 18

{
  "id": "MLC-T-CHM-012304",
  "term": "Trisomy 18",
  "field": "Chemistry",
  "definition": "A genetic disorder caused by the presence of an extra copy of chromosome 18 in some or all cells of the body. This chromosomal abnormality, also known as Edwards syndrome, results in severe developmental delays and congenital malformations affecting multiple organ systems. Infants born with trisomy 18 have a significantly reduced life expectancy, with many not surviving beyond the first year.",
  "synonyms": [
    "Edwards syndrome"
  ],
  "subject": "Chemistry and Human Health",
  "see_also": [
    "congenital malformation"
  ],
  "references": [
    "PAC, 2016, 88, 713. 'Glossary of terms used in developmental and reproductive toxicology (IUPAC Recommendations 2016)' on page 815 (https://doi.org/10.1515/pac-2015-1202)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/trisomy-18/"
}