Trisomy 8

{
  "id": "MLC-T-CHM-012306",
  "term": "Trisomy 8",
  "field": "Chemistry",
  "definition": "A chromosomal condition in which there is an extra copy of chromosome 8. A complete trisomy 8 is almost always lost as an early miscarriage, so people born with it are nearly all mosaic, with the extra chromosome in only some of their cells. Mosaic trisomy 8, called Warkany syndrome 2, causes variable features such as mild to moderate intellectual disability, deep palmar and plantar creases, and skeletal and kidney anomalies.",
  "synonyms": [
    "Warkany syndrome 2"
  ],
  "subject": "Chemistry and Human Health",
  "see_also": [
    "craniofacial",
    "mosaicism",
    "trisomy"
  ],
  "references": [
    "PAC, 2016, 88, 713. 'Glossary of terms used in developmental and reproductive toxicology (IUPAC Recommendations 2016)' on page 815 (https://doi.org/10.1515/pac-2015-1202)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/trisomy-8/"
}