Wernicke-Korsakoff syndrome

{
  "id": "MLC-T-CHM-012677",
  "term": "Wernicke-Korsakoff syndrome",
  "field": "Chemistry",
  "definition": "A neurological disorder resulting from severe thiamine (vitamin B1) deficiency, primarily affecting individuals with chronic alcoholism. It presents as two distinct stages: Wernicke encephalopathy, characterized by confusion, ataxia, and ophthalmoplegia, followed by Korsakoff syndrome, which involves severe memory impairment and confabulation. Treatment involves thiamine supplementation.",
  "synonyms": [
    "alcoholic encephalopathy"
  ],
  "subject": "Chemistry and Human Health",
  "see_also": [
    "agnosia",
    "aphasia",
    "apraxia",
    "encephalopathy",
    "psychosis"
  ],
  "references": [
    "PAC, 2015, 87, 841. 'IUPAC Glossary of terms used in neurotoxicology (IUPAC Recommendations 2015)' on page 916 (https://doi.org/10.1515/pac-2015-0103)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/wernicke-korsakoff-syndrome/"
}