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Acetonides

Term · Chemistry · MLC-T-CHM-000122

Cyclic acetals or ketals formed by the reaction of a 1,2-diol or 1,3-diol with acetone. These compounds are commonly used as protecting groups for diols in organic synthesis due to their ease of formation and removal under mild acidic conditions. The five-membered or six-membered ring structure provides steric hindrance, influencing reactivity at other parts of the molecule.

Table 1. Record
IdentifierMLC-T-CHM-000122
FieldChemistry
SubjectOrganic and Biomolecular Chemistry
ReferencesPAC, 1995, 67, 1307. 'Glossary of class names of organic compounds and reactivity intermediates based on structure (IUPAC Recommendations 1995)' on page 1311 (https://doi.org/10.1351/pac199567081307)
See alsoAcetals; Diols
Record as JSON
{
  "id": "MLC-T-CHM-000122",
  "term": "Acetonides",
  "field": "Chemistry",
  "definition": "Cyclic acetals or ketals formed by the reaction of a 1,2-diol or 1,3-diol with acetone. These compounds are commonly used as protecting groups for diols in organic synthesis due to their ease of formation and removal under mild acidic conditions. The five-membered or six-membered ring structure provides steric hindrance, influencing reactivity at other parts of the molecule.",
  "subject": "Organic and Biomolecular Chemistry",
  "see_also": [
    "acetals",
    "diols"
  ],
  "references": [
    "PAC, 1995, 67, 1307. 'Glossary of class names of organic compounds and reactivity intermediates based on structure (IUPAC Recommendations 1995)' on page 1311 (https://doi.org/10.1351/pac199567081307)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/acetonides/"
}

Record 127 of 13,676 in Chemistry terminology (MLC-0109). Request the full dataset.